Jews are more predisposed to colorectal cancer but there is a shortfall in funding and a lack of desire to change

As someone who two years ago was diagnosed with colorectal cancer and who, by the grace of HaShem and an outstanding consultant and surgeon was cured, I feel an overwhelming moral responsibility to urge people to look out for symptoms of colon/ bowel cancer before it is too late. It is a vile disease and each year we lose far too many good people. Yes the treatment is unpleasant but the alternative is far worse. The reality is those who seek treatment early can recover, even if, like me you delay for a while before going to your doctor. A  diagnosis is not an automatic death sentence.

So, let's look at the facts:

Good news and bad

First, the good news, among Americans under the age of 50, the overall cancer mortality has plummeted by 44% over the last quarter of a century and better diagnostic tools, along with a sharp reduction in smoking, help to explain why deaths from leukaemia as well as lung, breast and brain cancer are falling so dramatically.

Unfortunately, but inevitably there is also bad news - cancer mortality rates in the UK for those under 50 show a concerning trend and while overall cancer deaths are falling, incidences in under-50s have risen by 24% since 1995. Approximately 6,000 younger adults die from cancer annually in the UK, with early-onset bowel cancer mortality projected to rise significantly. In addition, colorectal cancer has risen 1.1% annually since 2005  advancing it from the fifth most common cause of cancer death in the early 1990s to second place today, 

Of even more concern is the fact the data shows how Jews, in particular should be especially alarmed as the research has shown how people of Ashkenazi, or Eastern European Jewish descent are likely to be two or three times more likely to develop colorectal cancer than nearly any other ethnic grouping.

According to the Norton and Elaine Sarnoff Center for Jewish Genetics, "Individuals of Ashkenazi Jewish ancestry have among the highest rates of colorectal cancer (CRC) of any ethnic group. In the general population, the lifetime risk of CRC is about five percent. In the Ashkenazi Jewish populations, this risk is two to three times greater than the general population.

About 10 percent of colorectal cancer is hereditary and within these two known cancer syndromes account for a significant proportion of hereditary colorectal cancer. However, having a cancer gene mutation does not mean a person will definitely have cancer, but it does increase their cancer risk. 

                   Alan Herman , National Executive Director of ICRF and a cancer survivor

According to  Alan Herman, the executive director of ICRF, which is the largest non-governmental funding resource for cancer research in Israel. “Colorectal cancer is rising at an alarming rate among young adults, challenging long-held assumptions about who is at risk ... These realities make research more urgent than ever.  By funding Israel’s most promising cancer scientists, the ICRF is driving discoveries that could lead to earlier detection, better treatments and ultimately save lives.”

Indeed, Israel has been very much at the heart of research into colorectal cancer. For example, Irit Ben-Aharon, is a medical oncologist specialising in gastrointestinal cancers and is Director of the Fishman Oncology Centre at Haifa’s Rambam Health Care Campus and also heads the European Organisation for Research and Treatment of Cancer task force for young-onset gastrointestinal cancer.

“There’s been an increase in the past three decades of early-onset colorectal cancer, and we don’t really know the reason,” she said. “Only 15% to 20% of these cases are hereditary; the rest came out of the blue.”

There has long been a belief that eating red meat and, in particular highly processed meats such as hot dogs and sausages is a major risk factor in early-onset colorectal cancer. However, Ben-Aharon remains unconvinced. "I don’t think it’s diet only — it’s multi-factorial,” she argues. “When you look at the data, if it would have been only diet, you’d not see the incidence of early-onset colorectal cancer rising all over the world. Diets are different in the U.S., Japan and Scandinavia, yet you see this increasing trend everywhere, and we probably would have seen a much higher incidence, as many people eat ultra-processed food and don’t develop colorectal cancer.”

Of major interest is her belief that bacteria may play a part in causing colorectal cancer., “Some toxins from specific bacteria have been shown to have increased levels in cases of early-onset colorectal cancer, implying these bacteria may induce cancer. Also, there is evidence linking increased risk due to exposure to specific pesticides.”

With regard to prevalence of colorectal cancer amongst Jews she has argued it is more common because Ashkenazi Jews are genetically predisposed to the disease, though not necessarily to the early-onset form of CRC.

“Environmental factors such as diet and other exposures like plastic and pesticides — and the combination with specific predisposition and host features such as microbiome and other pathways — may underlie this trend,” she said.

“Elucidating the interplay between environmental factors and unique features of patients predisposed to developing cancer at an early age would allow us to delineate the high-risk population,” she added. 

Irit Ben-Aharon is a medical oncologist specializing in gastrointestinal cancers. (Courtesy)

Hope for more effective and less toxic treatment

Drug discovery expert Professor Nir London works at Rehovot’s Weizmann Institute of Science as well as being the president of the Israel Chemical Society’s medicinal chemistry section.

                                                              Professor Nir London

“Many cancers are driven by specific mutations, which we call driver mutations. They tend to appear in the same types of cancers,” argues Professor London, “If a particular cell gains this mutation, it has a high propensity to transform into a cancerous cell. Such cancers get addicted to the mutation, so if you inhibit a protein with this mutation, you’ll have a way to mitigate the cancer’s growth. It’s a soft spot.”

“Not all colorectal cancers are the same,” London said. “We are focusing on developing drugs that are specific to a vulnerability found in about 13% of CRC patients. If successful, this could bring hope to hundreds of thousands of patients.”

In other research, Gilad Bachrach, who teaches at Hebrew University-Hadassah’s Institute of Dental Science in Jerusalem has focussed  on oncobacteriology — the study of bacteria as a treatment for cancer.

“Cancer has been treated by surgery and then by chemotherapy, radiotherapy and, most recently, immunotherapy. We believe bacteria therapy can be the next potential option in cancer treatment,” Bachrach said.

“We know bacteria are involved in cancer promotion, as well as anti-cancer activities,” he added. “Now the challenge is to harness bacteria for cancer detection and therapy.”

Ultimately, he said, “surgery, radiotherapy, chemotherapy and immunotherapy are established cancer treatments. My hope is that using bacteria to identify and target cancer will become the next major breakthrough in the field.”

Now, I cannot speak for other people who have experienced treatment for cancer, so here I can only speak for myself. Chemotherapy felt like being hit by a bus and while after only six weeks my cancer was substantially reduced, the treatment process was debilitating and unpleasant with symptoms that, in my case included extreme exhaustion, loss of appetite, inabillity to stand cold weather, nausea and quite severe anaemia. In addition, as a diabetic, glucose levels that had once been previously stable suddenly went out of control resulting in an urgent trip to the A&E department.. 

So any new treatment offering a significant improvement to general wellness can only be of benefit to the patient.

Political constraints

While scientific discoveries like those shown above give us all hope, all is not well in the implementation of cancer healthcare delivery. In the USA, there are clear budget shortfalls, exacerbated by projected reductions in federal funding for the National Institutes of Health (NIH) and National Cancer Institute (NCI), resulting in delays in colorectal cancer treatment and stalling research,  forcing clinical trial cuts across the USA. These fiscal constraints have resulted in treatment delays of four weeks or more for patients, allowing tumours to spread.

Furthermore, chemotherapy costs in the USA typically range from $1,000 to over $12,000 per month for drugs alone, with total annual treatment often exceeding $100,000. As a result total costs for the patient, including administration and supportive care, can lead (depending on insurance plans) to high out-of-pocket expenses of anything from $5,000 to $10,000+ annually) even with insurance. 

Meanwhile, in the UK, cancer cases are increasing, and cancer care could add £14.4bn to UK health spending annually by 2050, according to the latest OECD modelling. Add to this a lack of trained staff resulting in an NHS unable to deliver timely, high-quality care and diagnostic services. All these issues are further complicated by budgetary constraints that have led to the removal of some drugs from the Cancer Drugs Fund (CDF), sparking concerns about access to innovative treatments., 

So while we have outstanding breakthroughs happening across the world and I have only concentrated today on Israeli innovation, we have neither the practical facilities or the budget to implement these developments and until there is a willingness to bring about significant change across health provision internationally people will die unnecessarily.

So, should we be concerned? Well clearly any illness affecting Jews more than the rest of the population and more needs to be done to protect us but I'm not calling for armed rebellion or revolution her. The solution is much simpler and in our own hands.

A commercial FITT test is available to buy through your pharmacy or you csn ask your doctor. They only cost £60 or so, making them.reasonably affordable

 In addition, my US readers have the additional benefit of being urged to have occasional colonoscopies that can detect this form of cancer.

The bottom line is don't sit by and do nothing - the price of peace is eternal vigilance.

 

 

 

Have we become frogs in the water

In 1933, about 600,000 Jews lived in Germany, less than one percent of the total population. Most Jews in Germany were proud to be Germans, citizens of a country that had produced many great poets, writers, musicians, and artists. More than 100,000 German Jews had served in the German army during World War l and many were decorated for bravery.

Jews held important positions in government and taught in Germany's renowned universities. Of the 38 Nobel Prizes won by German writers and scientists between 1905 and 1936, 14 went to Jews. Marriage between Jews and non-Jews was becoming more common. Although German Jews continued to encounter some discrimination in their social lives and professional careers, many were confident of their future as Germans. They spoke the German language and regarded Germany as their home.

On 1st April 1933, the Nazis announced their boycott of Jewish businesses and professionals. Sturmabteilung, or SA, officers stood outside Jewish-owned businesses, intimidating them, and signs were posted that read, “The Jews are our misfortune” and “Don’t buy from Jews.”

The boycott was both a reprisal and an act of revenge against  Greuelpropaganda (atrocity stories) that German and foreign Jews, assisted by foreign journalists, were allegedly circulating in the international press to damage Nazi Germany's reputation. Germans to shame non-Jews who continued to patronise Jewish businesses. While the boycott lasted only a few days, it marked the beginning of the systematic targeting and discrimination of Jews in Nazi Germany.

The boycott was a countermeasure to an appeal from Jewish organisations in the United States to boycott German products. They wanted to protest against the mistreatment and discrimination of Jews in Germany. The boycott in Germany was not a great success. Many Germans did not care much, one way or the other, and the foreign press condemned the action. It was still an important moment in the development of anti-Jewish measures, though. 

For the first time, the Nazis showed clearly that they wanted to make life impossible for the Jews. Although the national boycott operation, organized by local Nazi party chiefs, lasted only one day and was ignored by many individual Germans who continued to shop in Jewish-owned stores, it marked the beginning of a nationwide campaign by the Nazi Party against the entire German Jewish population. 

A week later, the government passed a law restricting employment in the civil service to "Aryans." Jewish government workers, including teachers in public schools and universities, were fired. 

The modern day bpycott and the 'New' Neo-Nazism

A little over 90 years later Jewish companies and companies willing to sell Israeli products or have premises in Israel again face a boycott. Nothing has changed. Violent SS and SA troopers in their black or brown uniforms have been replaced by thuggish pro-Palestinian keffiyeh wearing neo Nazi-like bigots, who damage property, commit vandalism or, more dangerously and shamelessly threaten Jews or pro-Israel supporters.

Don't believe me? How about a pro-Palestinian rally held in the USA on 14th December, 2023 in front of Townhouse, an upscale restaurant and bar in downtown Detroit, led its owner to contact law enforcement and increase security. In social media posts, people reported hearing  one speaker say: "How many kids did you kill today?.There are dozens, if not hundreds more examples I could have offered.

Meanwhile in the UK and Europe it is no better - take the protest against Miznon Notting Hill restaurant in London, the gang attack on HaMakom cafe in Leipzig on Wednesday, the unionization against New York City Bread's Bakery participation in Israeli events, and the closure of the Tantura restaurant in Lisbon. All caused by violent extremists, these new neo-"Nazis". eager to perpetuate their inheritance of threat fand violence against Jews.

The illegitimacy of the BDS Movement

Of course, the BDS movement is in very large part at the heart at this antisemitic campaign and justify their campaign by comparing their "cause" to the fight to overthrow South African apartheid, but even a cursory glance shows overwhelmingly an absence of integrity in the BDS Movement  Take a few of the following examples:

Elbit Systems (Bristol, UK): The most prominent target is Elbit's facility near Bristol. In August 2024, protesters used a van as a battering ram to enter the site, causing approximately £1 million ($1.4 million) in damage, including smashing equipment and spraying red paint.

Other Defence Targets: Activists have targeted Thalesn Glasgow and Instro Precision in Kent. Blockades have also been organized at companies like Eaton Mission Systems in Dorset

Meanwhile in the USA:

Restaurants and Retail: The Philadelphia-based falafel shop Goldie was targeted by protestors over its owner's donations to an Israeli ambulance service. Similarly, Philadelphia restaurant Laser Wolf faced protests, and other Middle Eastern food businesses, such as New York City’s Ayat reported receiving abusive calls and negative reviews.

Defence Contractors: Companies supplying military equipment to Israel, such as Lockheed Martin (which produces F-35I fighter jets), have faced protests from groups demanding a halt to arms sales.

Tech and Financial Firms: Major U.S. tech firms including Microsoft, Amazon, Google and Meta have been accused by activists of supporting Israeli government activities through cloud computing and AI technology. Activists have also targeted financial institutions like Citibank or alleged financial links to Israeli security operations.

Israeli-Linked Manufacturers: Agilite an Israeli tactical gear manufacturer with U.S. retail locations, was flagged for advertising its products' use by the Israeli military in Gaza.

Political Comment

In short, the evidence is clear - we are like frogs in the water (drop a frog in hot water and it will  jump out, but put it in cold water slowly and heat it up then the frog will stay until it perishes) and nobody is helping us. In the US the view appears to be that Europe has fallen but we (ie America) are safe.. Are you? Look at the data and you will see your situation is as bad - businesses boycotted or vandalised, visible Jewish people attacked  and synagogues vulnerable to arson attacks or worse, shootings. You are no different,

Meanwhile in the UK and most of Europe things are far from good and there isn't a single political leader standing in our defence - look at Starmer, Macron or Pedro Sanchez. Like Europe of 1933 they are only concerned for themselves. Remember, Jews didn't start facing persecution when the Final Solution was enacted, it happened years before - and barely a soul said anything - much like today.

So what should we do? For many aliyah is a perfect solution, but after some thought it is not an option I will choose and it's not because of a lack of love for Israel. It is because until my last breath I intend to stay and fight. I will not be silent about what is happening, I will shout from the tallest rooftop and expose the dishonesty amongst our enemies; it is because I will face the pro-Pallies head on and attack their vile antisemitic and neo-Nazi rhetoric and show it for what it is; I will face and expose their shameful deceit in the passionate belief that truth and honesty will eventually prevail - and if I fail, I will be able to face those who might judge me and say at least I tried.

Chag Pesach Sameach.

Israel passes controversial death penalty law

 On Tuesday night, the Israeli Knesset enacted legislation requiring the death penalty for all West Bank Palestinians convicted of carrying out deadly terror attacks. Of course, the broader debate over the legitimacy of capital punishment is an emotive one and will be discussed later. The US has had a long term affinity for capital and the law allows 27 states to apply it, while the UK abolished it in 1960.

The new Israeli law has triggered predictable outrage abroad and deep debate at home. But beyond the headlines, the story is not just about capital punishment. It is about how terrorism, justice, and narrative framing collide and how those collisions are interpreted very differently depending on the lens. While some of the criticism is a legitimate part of the debate, there has also been a predictable international media reaction: alarmist headlines, sweeping generalizations, and, in some cases, outright misinformation.

But a closer reading of the legislation and of the reporting itself reveals a far narrower, more complex reality than many news  outlets would have readers believe.

Not “Palestinians” — Terrorists Convicted of Murder

A striking number of headlines refer broadly to “Palestinians,” implying that the law applies collectively to an entire population, but this is not the case..

A similar story has been seen in other newspapers.

The UK Telegraph newspaper headline completely ignores the fact the law focuses exclusively on terrorists who have murdered innocent civilians, not the average Palestinian.

The new law targets a specific category of perpetrators: terrorists who intentionally kill a person as part of an act of terrorism. It is not applicable to all Palestinians, nor even to all individuals involved in terrorism. Those whose actions do not result in fatalities are not subject to the death penalty under this law.

Yet by stripping away that crucial distinction, media coverage transforms a narrowly defined legal measure into what appears to be a sweeping policy of collective punishment. Nothing new here, as most newspaper in both the US and UK love the opportunity to berate Israel,

That framing is misleading.

The law is NOT retroactive — and not about “thousands of prisoners”

Another claim circulating is that the law could be used against the thousands of Palestinians currently held in Israeli prisons.

Again, that is not the case. This law will only affect terrorists convicted of intentionally killing innocent people, not thousands of inmates.

Furthermore, the law cannot be applied retroactively. It applies only to future convictions meeting a specific criteria. Existing prisoners — regardless of their crimes for which they were convicted — are not affected.

By omitting this basic legal principle, some reporting inevitably has left audiences with the false impression that Israel is preparing to execute large numbers of current detainees but this is not the case

A Country Deeply Divided on the Issue

Another element missing from much of the coverage is the significant domestic debate prevalent Israel itself. Indeed, there is no national consensus behind the law.

Opposition figures, legal experts, and segments of the public have, and are continuing to raise major concerns — from moral objections to questions about deterrence and potential consequences. Even within Israel’s political and security establishment, the issue has long been contentious.

In other words, this is not the action of a monolithic state imposing an uncontested policy despite i9mplications raised by external media.. It is the product of a democratic system grappling openly and contentiously with a deeply sensitive issue.

Furthermore, this law has been passed against the backdrop of the Hamas October 7 massacre. Beyond emotive calls to deal with future terrorist threats or to apply some form of deterrence, there is a very practical reality that Israel has faced. Let us never forget, Israeli hostages were kidnapped and held in Gaza to be exchanged for thousands of Palestinian prisoners.

It is hard to forget that in a previous prisoner exchange, The now eradicated Hamas leader and mastermind of October 7, Yahya Sinwar was among those released  and for some Israelis, the death penalty may reduce the risk of such a murderer being freed in future.

A Law That Will Face Legal Scrutiny

So transparently the legal debate is far from over and Israel’s legal system, anchored by an independent judiciary, is expected to examine the law in detail. Any attempt to implement it will likely face rigorous judicial review.

Yet this reality — that the law will be tested, challenged, and potentially constrained through legal mechanisms is largely absent from coverage that prefers a more simplistic and largely anti:Israel narrative.

In addition, while death by hanging may be the default punishment for West Bank residents convicted of deadly terrorist acts by military courts, judges can opt for life imprisonment under vaguely defined “special circumstances.” Also, the sentence would still require a simple majority of judges, thus avoiding a unilateral decision on a matter of such gravity.

It is worth noting that the law was watered down to ensure it would not go any further than any similar laws enacted under U.S. legislation.

The Bottom Line

The death penalty law raises serious questions. Israelis themselves are debating them.

But the portrayal of the law as a sweeping, discriminatory measure targeting Palestinians as a whole — or as a tool poised to be applied to thousands of existing prisoners — does not withstand scrutiny.

It is a narrower, prospective measure aimed at a specific category of deadly terrorism.

And once again, the gap between what the law says and how it is reported tells its own story..

Political Comment

The new legislation raises a number of political, legal, religious and ethical issues. Now I am very far from as religious or Talmudic scholar so, if I may I will leave that issue to others more learned than me.

But on the political arena I think Israel is making a grave mistake. Internationally the country is not at its strongest and, thanks to a major media and social media campaign the "Palestinian" movement to sway opinion against the country, It is therefore inevitable that when a Palestinian terrorist kills an Israeli and is sentenced to death they could well be perceived as martyrs and undoubtedly anti-Zionists will create a mass campaign against the country.

Secondly, the country is an active war against Iran - a war that could see the US leaving without completing all of the strategic goals required. If that happens Israel will need to be united in what could become a prolonged war with Iran.

Third, it is inconceivable that the PA will recruit terrorists willing to kill Jews and become martyrs to "the cause" and promote their illegitimate campaign. While Iranian money will not be available, there are enough funds available to mount a prolonged campaign.

At an ethical issue there are further problems. The only capital death on Israeli soil was Adolf Eichmann and the nation has a proud history of avoiding capital sentencing despite countless sentencing. If this is to change courts will have to establish unquestionable guilt and internationally there are countless examples of how, despite stringent safeguards mistakes have been made.

So, in short I fear this new law will be a terrible mistake for a country that prides itself for being the only democracy in the Middle East and while the nation is very from an apartheid state, having legislation that punishes according to race leaves Israel vulnerable to accusations of having different rules for Palestinians than Jews. Creating laws based on vengeance and hatred are not the solution - we win when we show even our enemies that we will not succumb to bitterness and revenge. Payback and reprisal will not make Israelis safer.

The unpleasant case of Green antisemitism

 The leader of the Green Party of England and Wales, who is Jewish, took to social media after an article from the Daily Mail quoted one of his family members saying he is "the leader of the future Islamic party of Britain".

The article featured three extended family members who Polanski with whom he has no contact.

Responding, Polanski pointed out that he is currently the only Jewish person in charge of a political party, adding: "The Daily Mail have been and always will be my enemy – they historically supported fascists and continue to do so.

"I'll take no lectures from them on antisemitism."

A Green Party spokesman also hit out at the article, saying: "Zack is one of five Jewish leaders of a political party in British history and the harassment he has received since being elected is patently antisemitic.

"Reporting like this demeans the press and our democracy." 

Responding to backlash, Nicole Lampert - the journalist who wrote the piece and who is Jewish herself - denied that she was "going after" Polanski's family and said those she had spoken to were "frightened by the Jew hate in your party"

She continued: "They are frightened by what you have given the green light to ... While you once fought Jew hatred, now you indulge it because, as we both see, it is popular."

"Other political groups have discovered this in the past," she added.

Polanski responded accusing the journalist of "parasitic behaviour" and dismissing the story as "daily nonsense".

I find a strange irony here - a political leader whose party has patently expressed anti-Israel and, by default anti-Zionist comments now finds it necessary to defend itself from what it calls antisemitic attacks. Personally, I call that "Jewish when needed".

Sorry Zack, it won't work!

You and your ridiculous little party have brought this on yourselves and I have no sympathy. Historically the Greens have always done badly in General Elections and I see no evidence this will change. Remember, back in 1981 the Lib Dems were told by their then leader, David Steele " ... Prepare for government". Well, back in 2024 they only managed 72 MPs, a long way from government.

Be warned, the Greens are a vicious, nasty antisemitic party but, like a tiny stone in your shoe they will be thrown out and consigned to the dustbin